How different are luminal A and basal breast cancers?
نویسندگان
چکیده
منابع مشابه
Integrated profiling of basal and luminal breast cancers.
Basal and luminal are two molecular subtypes of breast cancer with opposite histoclinical features. We report a combined, high-resolution analysis of genome copy number and gene expression in primary basal and luminal breast cancers. First, we identified and compared genomic alterations in 45 basal and 48 luminal tumors by using 244K oligonucleotide array comparative genomic hybridization (aCGH...
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Basal-like breast cancers have several well-characterized distinguishing molecular features, but most of these are features of the cancer cells themselves. The unique stromal–epithelial interactions, and more generally, microenvironmental features of basal-like breast cancers have not been well characterized. To identify characteristic microenvironment features of basal-like breast cancer, we p...
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(1) Molecular Oncology Program, Department of Surgery and Sylvester Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136 (2) Lineberger Cancer Center (3) Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 275997295 (4) Present address: Department of Biomedical Sciences, University at Albany, Rensselaer, NY 12144. (5) These authors cont...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2009
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.24055